La maladie de Parkinson au Canada (serveur d'exploration)

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Medial forebrain bundle stimulation as a pathophysiological mechanism for hypomania in subthalamic nucleus deep brain stimulation for Parkinson's disease.

Identifieur interne : 001E18 ( Main/Exploration ); précédent : 001E17; suivant : 001E19

Medial forebrain bundle stimulation as a pathophysiological mechanism for hypomania in subthalamic nucleus deep brain stimulation for Parkinson's disease.

Auteurs : Volker A. Coenen [Canada] ; Christopher R. Honey ; Trevor Hurwitz ; Ahmed A. Rahman ; Jacqueline Mcmaster ; Uli Bürgel ; Burkhard M Dler

Source :

RBID : pubmed:19487890

English descriptors

Abstract

Hypomania accounts for approximately 4% to 13% of psychotropic adverse events during subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson's disease. Diffusion of current into the inferior and medial "limbic" STN is often reported to be the cause. We suggest a different explanation, in which the coactivation of the medial forebrain bundle (MFB), outside the STN, leads to hypomania during STN DBS.

DOI: 10.1227/01.NEU.0000345631.54446.06
PubMed: 19487890


Affiliations:


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Le document en format XML

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